Breast Cancer Phenotype Associated With Li-Fraumeni Syndrome: A Brazilian Cohort Enriched by TP53 p.R337H Carriers

Breast cancer (BC) is the most prevalent malignancy in women with Li-Fraumeni syndrome (LFS). The literature on BC in LFS is limited due to its rarity worldwide. A TP53 founder pathogenic variant (c.1010G>A; p.R337H) is responsible for the higher prevalence of this syndrome among women of Brazili...

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Detalles Bibliográficos
Autores principales: Sandoval, Renata Lazari, Polidorio, Natalia, Leite, Ana Carolina Rathsam, Cartaxo, Mariana, Pisani, Janina Pontes, Quirino, Carla Vanessa, Cezana, Loureno, Pereira, Natálya Gonçalves, Pereira, Allan Andresson Lima, Rossi, Benedito Mauro, Achatz, Maria Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966034/
https://www.ncbi.nlm.nih.gov/pubmed/35371985
http://dx.doi.org/10.3389/fonc.2022.836937

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966034/
https://www.ncbi.nlm.nih.gov/pubmed/35371985
http://dx.doi.org/10.3389/fonc.2022.836937

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