Structure-based design and construction of a synthetic phage display nanobody library

OBJECTIVE: To design and construct a new synthetic nanobody library using a structure-based approach that seeks to maintain high protein stability and increase the number of functional variants within the combinatorial space of mutations. RESULTS: Synthetic nanobody (Nb) libraries are emerging as an...

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Detalles Bibliográficos
Autores principales: Moreno, Ernesto, Valdés-Tresanco, Mario S., Molina-Zapata, Andrea, Sánchez-Ramos, Oliberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966178/
https://www.ncbi.nlm.nih.gov/pubmed/35351202
http://dx.doi.org/10.1186/s13104-022-06001-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966178/
https://www.ncbi.nlm.nih.gov/pubmed/35351202
http://dx.doi.org/10.1186/s13104-022-06001-7

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