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The amyloid peptide β disrupts intercellular junctions and increases endothelial permeability in a NADPH oxidase 1-dependent manner

Alzheimer's disease is the most common form of dementia and is associated with the accumulation of amyloid peptide β in the brain parenchyma. Vascular damage and microvascular thrombosis contribute to the neuronal degeneration and the loss of brain function typical of this disease. In this stud...

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Detalles Bibliográficos
Autores principales: Tarafdar, Anuradha, Wolska, Nina, Krisp, Christoph, Schlüter, Hartmut, Pula, Giordano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966210/
https://www.ncbi.nlm.nih.gov/pubmed/35358850
http://dx.doi.org/10.1016/j.redox.2022.102287