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Identification of blood-based key biomarker and immune infiltration in Immunoglobulin A nephropathy by comprehensive bioinformatics analysis and a cohort validation

BACKGROUND: To identify the critical genes in the onset and progression of Immunoglobulin A nephropathy (IgAN) and to explore its immune cell infiltration feature. METHODS: Differentially expressed genes (DEGs) were firstly screened from 1 blood-derived dataset GSE73953 and a glomerulus derived data...

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Detalles Bibliográficos
Autores principales: Xu, Jie, Shen, Xiahong, Wei, Xing, Ding, Jie, Yuan, Jiaojiao, Weng, Zhen, He, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966267/
https://www.ncbi.nlm.nih.gov/pubmed/35351150
http://dx.doi.org/10.1186/s12967-022-03330-w