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Voriconazole injection may induce delayed methotrexate excretion: a case report and experimental study

BACKGROUND: We report a case of delayed excretion of methotrexate (MTX) in a pediatric patient on high-dose MTX therapy in response to a change in the concomitant dosage of voriconazole from oral to intravenous. As the intravenous, but not the oral formulation of voriconazole includes sulfobutylethe...

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Detalles Bibliográficos
Autores principales: Watahiki, Daisuke, Saito, Daisuke, Nishida, Naonori, Tsuri, Hiroyuki, Nomura, Keiko, Adachi, Yuichi, Taguchi, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966289/
https://www.ncbi.nlm.nih.gov/pubmed/35351207
http://dx.doi.org/10.1186/s40780-022-00240-3