Downregulation of ADAM17 in pediatric immune thrombocytopenia impairs proplatelet formation

BACKGROUND: Immune thrombocytopenia (ITP) is the most common etiology of acquired thrombocytopenia diseases in children. ITP is characterized by the immune-mediated decreased formation and excessive destruction of platelets. The pathogenesis and management of pediatric ITP are distinct from adult IT...

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Detalles Bibliográficos
Autores principales: Wang, Qi, Wei, Jia, Jia, Xi, Feng, Xiao, Ji, Zhenghua, Ji, Xueqiang, Shao, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966352/
https://www.ncbi.nlm.nih.gov/pubmed/35354403
http://dx.doi.org/10.1186/s12887-022-03237-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966352/
https://www.ncbi.nlm.nih.gov/pubmed/35354403
http://dx.doi.org/10.1186/s12887-022-03237-x

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