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Downregulation of ADAM17 in pediatric immune thrombocytopenia impairs proplatelet formation

BACKGROUND: Immune thrombocytopenia (ITP) is the most common etiology of acquired thrombocytopenia diseases in children. ITP is characterized by the immune-mediated decreased formation and excessive destruction of platelets. The pathogenesis and management of pediatric ITP are distinct from adult IT...

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Detalles Bibliográficos
Autores principales:	Wang, Qi, Wei, Jia, Jia, Xi, Feng, Xiao, Ji, Zhenghua, Ji, Xueqiang, Shao, Xuejun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966352/ https://www.ncbi.nlm.nih.gov/pubmed/35354403 http://dx.doi.org/10.1186/s12887-022-03237-x

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