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Structural Basis for the Propagation of Homing Endonuclease-Associated Inteins

Inteins catalyze their removal from a host protein through protein splicing. Inteins that contain an additional site-specific endonuclease domain display genetic mobility via a process termed “homing” and thereby act as selfish DNA elements. We elucidated the crystal structures of two archaeal intei...

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Detalles Bibliográficos
Autores principales: Beyer, Hannes M., Iwaï, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966425/
https://www.ncbi.nlm.nih.gov/pubmed/35372505
http://dx.doi.org/10.3389/fmolb.2022.855511