Development of an exoglycosidase plate-based assay for detecting α1-3,4 fucosylation biomarker in individuals with HNF1A-MODY

Maturity-onset diabetes of the young due to hepatocyte nuclear factor-1 alpha variants (HNF1A-MODY) causes monogenic diabetes. Individuals carrying damaging variants in HNF1A show decreased levels of α1-3,4 fucosylation, as demonstrated on antennary fucosylation of blood plasma N-glycans. The excell...

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Detalles Bibliográficos
Autores principales: Demus, Daniel, Urbanowicz, Paulina A, Gardner, Richard A, Wu, Haiyang, Juszczak, Agata, Štambuk, Tamara, Medvidović, Edita Pape, Owen, Katharine R, Gornik, Olga, Juge, Nathalie, Spencer, Daniel I R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Analytical Glycobiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966479/
https://www.ncbi.nlm.nih.gov/pubmed/34939081
http://dx.doi.org/10.1093/glycob/cwab107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966479/
https://www.ncbi.nlm.nih.gov/pubmed/34939081
http://dx.doi.org/10.1093/glycob/cwab107

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