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An in vivo Pig Model for Testing Novel Positron Emission Tomography Radioligands Targeting Cerebral Protein Aggregates

Positron emission tomography (PET) has become an essential clinical tool for diagnosing neurodegenerative diseases with abnormal accumulation of proteins like amyloid-β or tau. Despite many attempts, it has not been possible to develop an appropriate radioligand for imaging aggregated α-synuclein in...

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Detalles Bibliográficos
Autores principales: Raval, Nakul Ravi, Nasser, Arafat, Madsen, Clara Aabye, Beschorner, Natalie, Beaman, Emily Eufaula, Juhl, Morten, Lehel, Szabolcs, Palner, Mikael, Svarer, Claus, Plavén-Sigray, Pontus, Jørgensen, Louise Møller, Knudsen, Gitte Moos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966485/
https://www.ncbi.nlm.nih.gov/pubmed/35368260
http://dx.doi.org/10.3389/fnins.2022.847074