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An in vivo Pig Model for Testing Novel Positron Emission Tomography Radioligands Targeting Cerebral Protein Aggregates
Positron emission tomography (PET) has become an essential clinical tool for diagnosing neurodegenerative diseases with abnormal accumulation of proteins like amyloid-β or tau. Despite many attempts, it has not been possible to develop an appropriate radioligand for imaging aggregated α-synuclein in...
Autores principales: | Raval, Nakul Ravi, Nasser, Arafat, Madsen, Clara Aabye, Beschorner, Natalie, Beaman, Emily Eufaula, Juhl, Morten, Lehel, Szabolcs, Palner, Mikael, Svarer, Claus, Plavén-Sigray, Pontus, Jørgensen, Louise Møller, Knudsen, Gitte Moos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966485/ https://www.ncbi.nlm.nih.gov/pubmed/35368260 http://dx.doi.org/10.3389/fnins.2022.847074 |
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