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Pan-Cancer Analyses Identify the CTC1-STN1-TEN1 Complex as a Protective Factor and Predictive Biomarker for Immune Checkpoint Blockade in Cancer

The CTC1-STN1-TEN1 (CST) complex plays a crucial role in telomere replication and genome stability. However, the detailed mechanisms of CST regulation in cancer remain largely unknown. Here, we perform a comprehensive analysis of CST across 33 cancer types using multi-omic data from The Cancer Genom...

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Detalles Bibliográficos
Autores principales: Wang, Lishuai, Ma, Tengfei, Liu, Weijin, Li, Heping, Luo, Zhenhua, Feng, Xuyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966541/
https://www.ncbi.nlm.nih.gov/pubmed/35368664
http://dx.doi.org/10.3389/fgene.2022.859617