Oxindole synthesis via polar–radical crossover of ketene-derived amide enolates in a formal [3 + 2] cycloaddition

Herein we introduce a simple, efficient and transition-metal free method for the preparation of valuable and sterically hindered 3,3-disubstituted oxindoles via polar–radical crossover of ketene derived amide enolates. Various easily accessible N-alkyl and N-arylanilines are added to disubstituted k...

Descripción completa

Detalles Bibliográficos
Autores principales: Radhoff, Niklas, Studer, Armido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966637/
https://www.ncbi.nlm.nih.gov/pubmed/35432887
http://dx.doi.org/10.1039/d1sc07134c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966637/
https://www.ncbi.nlm.nih.gov/pubmed/35432887
http://dx.doi.org/10.1039/d1sc07134c

Ejemplares similares