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α-Branched amines through radical coupling with 2-azaallyl anions, redox active esters and alkenes
α-Branched amines are fundamental building blocks in a variety of natural products and pharmaceuticals. Herein is reported a unique cascade reaction that enables the preparation of α-branched amines bearing aryl or alkyl groups at the β- or γ-positions. The cascade is initiated by reduction of redox...
Autores principales: | Duan, Shengzu, Zi, Yujin, Wang, Lingling, Cong, Jielun, Chen, Wen, Li, Minyan, Zhang, Hongbin, Yang, Xiaodong, Walsh, Patrick J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966660/ https://www.ncbi.nlm.nih.gov/pubmed/35432903 http://dx.doi.org/10.1039/d2sc00500j |
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