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The degenerative impact of hyperglycemia on the structure and mechanics of developing murine intervertebral discs

INTRODUCTION: Diabetes has long been implicated as a major risk factor for intervertebral disc (IVD) degeneration, interfering with molecular signaling and matrix biochemistry, which ultimately aggravates the progression of the disease. Glucose content has been previously shown to influence structur...

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Detalles Bibliográficos
Autores principales: Lintz, Marianne, Walk, Remy E., Tang, Simon Y., Bonassar, Lawrence J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966876/
https://www.ncbi.nlm.nih.gov/pubmed/35386755
http://dx.doi.org/10.1002/jsp2.1191