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Loss of KCC2 in GABAergic Neurons Causes Seizures and an Imbalance of Cortical Interneurons
K-Cl transporter KCC2 is an important regulator of neuronal development and neuronal function at maturity. Through its canonical transporter role, KCC2 maintains inhibitory responses mediated by γ-aminobutyric acid (GABA) type A receptors. During development, late onset of KCC2 transporter activity...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966887/ https://www.ncbi.nlm.nih.gov/pubmed/35370549 http://dx.doi.org/10.3389/fnmol.2022.826427 |