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Functional proteomics of patient derived head and neck squamous cell carcinoma cells reveal novel applications of trametinib
In this study, we report a differential response of mitogen-activated protein kinase–kinase (MEK) inhibitor trametinib in 20 head and neck squamous cell carcinoma (HNSCC) patients’ tumor-derived cell cultures. Relatively sensitive and resistant cases to trametinib were identified using high throughp...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966983/ https://www.ncbi.nlm.nih.gov/pubmed/35343367 http://dx.doi.org/10.1080/15384047.2022.2055420 |