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Functional proteomics of patient derived head and neck squamous cell carcinoma cells reveal novel applications of trametinib

In this study, we report a differential response of mitogen-activated protein kinase–kinase (MEK) inhibitor trametinib in 20 head and neck squamous cell carcinoma (HNSCC) patients’ tumor-derived cell cultures. Relatively sensitive and resistant cases to trametinib were identified using high throughp...

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Detalles Bibliográficos
Autores principales:	Vigoda, Myles, Mathieson, Chase, Evans, Nathaniel, Hale, Carolyn, Jennings, Jennifer, Lucero, Olivia, Jeng, Sophia, Bottomly, Daniel, Clayburgh, Daniel, Andersen, Peter, Li, Ryan, Petrisor, Daniel, Tyner, Jeffrey W., McWeeney, Shannon, Kulesz-Martin, Molly
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966983/ https://www.ncbi.nlm.nih.gov/pubmed/35343367 http://dx.doi.org/10.1080/15384047.2022.2055420

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