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The voltage-gated Ca(2+) channel subunit α(2)δ-4 regulates locomotor behavior and sensorimotor gating in mice
Voltage-gated Ca(2+) channels are critical for the development and mature function of the nervous system. Variants in the CACNA2D4 gene encoding the α(2)δ-4 auxiliary subunit of these channels are associated with neuropsychiatric and neurodevelopmental disorders. α(2)δ-4 is prominently expressed in...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967030/ https://www.ncbi.nlm.nih.gov/pubmed/35353835 http://dx.doi.org/10.1371/journal.pone.0263197 |