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Phosphorylated TDP-43 aggregates in peripheral motor nerves of patients with amyotrophic lateral sclerosis

Phosphorylated TDP-43 (pTDP-43) aggregates in the cytoplasm of motor neurons and neuroglia in the brain are one of the pathological hallmarks of amyotrophic lateral sclerosis. Although the axons exceed the total volume of motor neuron soma by several orders of magnitude, systematic studies investiga...

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Detalles Bibliográficos
Autores principales: Riva, Nilo, Gentile, Francesco, Cerri, Federica, Gallia, Francesca, Podini, Paola, Dina, Giorgia, Falzone, Yuri Matteo, Fazio, Raffaella, Lunetta, Christian, Calvo, Andrea, Logroscino, Giancarlo, Lauria, Giuseppe, Corbo, Massimo, Iannaccone, Sandro, Chiò, Adriano, Lazzerini, Alberto, Nobile-Orazio, Eduardo, Filippi, Massimo, Quattrini, Angelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967102/
https://www.ncbi.nlm.nih.gov/pubmed/35076694
http://dx.doi.org/10.1093/brain/awab285