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Ndufs4 knockout mouse models of Leigh syndrome: pathophysiology and intervention

Mitochondria are small cellular constituents that generate cellular energy (ATP) by oxidative phosphorylation (OXPHOS). Dysfunction of these organelles is linked to a heterogeneous group of multisystemic disorders, including diabetes, cancer, ageing-related pathologies and rare mitochondrial disease...

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Detalles Bibliográficos
Autores principales: van de Wal, Melissa A E, Adjobo-Hermans, Merel J W, Keijer, Jaap, Schirris, Tom J J, Homberg, Judith R, Wieckowski, Mariusz R, Grefte, Sander, van Schothorst, Evert M, van Karnebeek, Clara, Quintana, Albert, Koopman, Werner J H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967107/
https://www.ncbi.nlm.nih.gov/pubmed/34849584
http://dx.doi.org/10.1093/brain/awab426