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Dual data and motif clustering improves the modeling and interpretation of phosphoproteomic data
Cell signaling is orchestrated in part through a network of protein kinases and phosphatases. Dysregulation of kinase signaling is widespread in diseases such as cancer and is readily targetable through inhibitors. Mass spectrometry-based analysis can provide a global view of kinase regulation, but...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967184/ https://www.ncbi.nlm.nih.gov/pubmed/35360705 http://dx.doi.org/10.1016/j.crmeth.2022.100167 |