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CDX2 downregulation in mouse mural trophectoderm during peri‐implantation is heteronomous, dependent on the YAP‐TEAD pathway and controlled by estrogen‐induced factors

PURPOSE: To investigate the transition of CDX2 expression patterns in mouse trophectoderm (TE) and its regulatory mechanisms during implantation. METHODS: Mouse E3.5–4.5 blastocysts were used to immunostain CDX2, YAP, TEAD4, and ESRRB. Endogenous estrogen signaling was perturbed by administrating es...

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Detalles Bibliográficos
Autores principales: Suzuki, Daisuke, Okura, Keitaro, Nagakura, Seina, Ogawa, Hidehiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967280/
https://www.ncbi.nlm.nih.gov/pubmed/35386376
http://dx.doi.org/10.1002/rmb2.12446