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Lipid Droplet-Related PLIN2 in CD68(+) Tumor-Associated Macrophage of Oral Squamous Cell Carcinoma: Implications for Cancer Prognosis and Immunotherapy

BACKGROUND: PLIN2 (adipose differentiation-related protein) belongs to the perilipin family and is a marker of lipid droplets (LDs). Numerous types of tumor exhibit a high PLIN2 level, but its tumorigenic or tumor-suppressive role has been in debate. Recently, LDs serve as innate immune hubs and sho...

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Detalles Bibliográficos
Autores principales: He, Yijia, Dong, Yuexin, Zhang, Xinwen, Ding, Zhuang, Song, Yuxian, Huang, Xiaofeng, Chen, Sheng, Wang, Zhiyong, Ni, Yanhong, Ding, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967322/
https://www.ncbi.nlm.nih.gov/pubmed/35372038
http://dx.doi.org/10.3389/fonc.2022.824235