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Fine Mapping of the MAP2K5 Region Identified rs7175517 as a Causal Variant Related to BMI in China and the United Kingdom Populations

Background: Genome-wide association studies (GWASs) have consistently identified MAP2K5 as an obesity susceptibility gene. To deepen our understanding of the potential causal genetic variants of this region, a fine-mapping study of MAP2K5 was conducted. Methods and Results: SNPs rs7175517 (G > A)...

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Detalles Bibliográficos
Autores principales: Lu, Ce, Wang, Hai-Jun, Song, Jie-Yun, Wang, Shuo, Li, Xue-Ying, Huang, Tao, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967323/
https://www.ncbi.nlm.nih.gov/pubmed/35368675
http://dx.doi.org/10.3389/fgene.2022.838685