Potential role of KRAB-ZFP binding and transcriptional states on DNA methylation of retroelements in human male germ cells

DNA methylation, repressive histone modifications, and PIWI-interacting RNAs are essential for controlling retroelement silencing in mammalian germ lines. Dysregulation of retroelement silencing is associated with male sterility. Although retroelement silencing mechanisms have been extensively studi...

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Detalles Bibliográficos
Autores principales: Fukuda, Kei, Makino, Yoshinori, Kaneko, Satoru, Shimura, Chikako, Okada, Yuki, Ichiyanagi, Kenji, Shinkai, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967385/
https://www.ncbi.nlm.nih.gov/pubmed/35315771
http://dx.doi.org/10.7554/eLife.76822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967385/
https://www.ncbi.nlm.nih.gov/pubmed/35315771
http://dx.doi.org/10.7554/eLife.76822

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