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Potential role of KRAB-ZFP binding and transcriptional states on DNA methylation of retroelements in human male germ cells
DNA methylation, repressive histone modifications, and PIWI-interacting RNAs are essential for controlling retroelement silencing in mammalian germ lines. Dysregulation of retroelement silencing is associated with male sterility. Although retroelement silencing mechanisms have been extensively studi...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967385/ https://www.ncbi.nlm.nih.gov/pubmed/35315771 http://dx.doi.org/10.7554/eLife.76822 |