Combination of Ascorbic Acid and Menadione Induces Cytotoxic Autophagy in Human Glioblastoma Cells

We investigated the ability of the ascorbic acid (AA) and menadione (MD) combination, the well-known reactive oxidative species- (ROS-) generating system, to induce autophagy in human U251 glioblastoma cells. A combination of AA and MD (AA+MD), in contrast to single treatments, induced necrosis-like...

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Detalles Bibliográficos
Autores principales: Despotović, Ana, Mirčić, Aleksandar, Misirlić-Denčić, Sonja, Harhaji-Trajković, Ljubica, Trajković, Vladimir, Zogović, Nevena, Tovilović-Kovačević, Gordana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967583/
https://www.ncbi.nlm.nih.gov/pubmed/35368869
http://dx.doi.org/10.1155/2022/2998132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967583/
https://www.ncbi.nlm.nih.gov/pubmed/35368869
http://dx.doi.org/10.1155/2022/2998132

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