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Doxycycline prevents blood–brain barrier dysfunction and microvascular hyperpermeability after traumatic brain injury

The main objective of this study was to determine the cellular and molecular effects of doxycycline on the blood–brain barrier (BBB) and protection against secondary injuries following traumatic brain injury (TBI). Microvascular hyperpermeability and cerebral edema resulting from BBB dysfunction aft...

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Detalles Bibliográficos
Autores principales: Robinson, Bobby D., Isbell, Claire L., Melge, Anu R., Lomas, Angela M., Shaji, Chinchusha Anasooya, Mohan, C. Gopi, Huang, Jason H., Tharakan, Binu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967830/
https://www.ncbi.nlm.nih.gov/pubmed/35354869
http://dx.doi.org/10.1038/s41598-022-09394-4