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Doxycycline prevents blood–brain barrier dysfunction and microvascular hyperpermeability after traumatic brain injury
The main objective of this study was to determine the cellular and molecular effects of doxycycline on the blood–brain barrier (BBB) and protection against secondary injuries following traumatic brain injury (TBI). Microvascular hyperpermeability and cerebral edema resulting from BBB dysfunction aft...
Autores principales: | Robinson, Bobby D., Isbell, Claire L., Melge, Anu R., Lomas, Angela M., Shaji, Chinchusha Anasooya, Mohan, C. Gopi, Huang, Jason H., Tharakan, Binu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967830/ https://www.ncbi.nlm.nih.gov/pubmed/35354869 http://dx.doi.org/10.1038/s41598-022-09394-4 |
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