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An original approach to measure ligand/receptor binding affinity in non-purified samples

Several biochemical and biophysical methods are available to determine ligand binding affinities between a biological target and its ligands, most of which require purification, labelling or surface immobilisation. These measurements, however, remain challenging in regards to membrane proteins, as p...

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Detalles Bibliográficos
Autores principales: Rascol, Estelle, Dufourquet, Anouk, Baccouch, Rim, Soule, Pierre, Alves, Isabel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967833/
https://www.ncbi.nlm.nih.gov/pubmed/35354858
http://dx.doi.org/10.1038/s41598-022-09217-6