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Sea anemone Bartholomea annulata venom inhibits voltage-gated Na(+) channels and activates GABA(A) receptors from mammals

Toxin production in nematocysts by Cnidaria phylum represents an important source of bioactive compounds. Using electrophysiology and, heterologous expression of mammalian ion channels in the Xenopus oocyte membrane, we identified two main effects produced by the sea anemone Bartholomea annulata ven...

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Detalles Bibliográficos
Autores principales: Colom-Casasnovas, Antònia, Garay, Edith, Cisneros-Mejorado, Abraham, Aguilar, Manuel B., Lazcano-Pérez, Fernando, Arellano, Rogelio O., Sánchez-Rodríguez, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967859/
https://www.ncbi.nlm.nih.gov/pubmed/35354863
http://dx.doi.org/10.1038/s41598-022-09339-x