Cargando…

Sea anemone Bartholomea annulata venom inhibits voltage-gated Na(+) channels and activates GABA(A) receptors from mammals

Toxin production in nematocysts by Cnidaria phylum represents an important source of bioactive compounds. Using electrophysiology and, heterologous expression of mammalian ion channels in the Xenopus oocyte membrane, we identified two main effects produced by the sea anemone Bartholomea annulata ven...

Descripción completa

Detalles Bibliográficos
Autores principales:	Colom-Casasnovas, Antònia, Garay, Edith, Cisneros-Mejorado, Abraham, Aguilar, Manuel B., Lazcano-Pérez, Fernando, Arellano, Rogelio O., Sánchez-Rodríguez, Judith
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967859/ https://www.ncbi.nlm.nih.gov/pubmed/35354863 http://dx.doi.org/10.1038/s41598-022-09339-x

Ejemplares similares

Comprehensive Analysis and Biological Characterization of Venom Components from Solitary Scoliid Wasp Campsomeriella annulata annulata
por: Alberto-Silva, Carlos, et al.
Publicado: (2021)

Therapeutic Potential of GABAergic Signaling in Myelin Plasticity and Repair
por: Reyes-Haro, Daniel, et al.
Publicado: (2021)

Activity of Palythoa caribaeorum Venom on Voltage-Gated Ion Channels in Mammalian Superior Cervical Ganglion Neurons
por: Lazcano-Pérez, Fernando, et al.
Publicado: (2016)

Micro and macroevolution of sea anemone venom phenotype
por: Smith, Edward G., et al.
Publicado: (2023)

Never, Ever Make an Enemy… Out of an Anemone: Transcriptomic Comparison of Clownfish Hosting Sea Anemone Venoms
por: Delgado, Alonso, et al.
Publicado: (2022)

Voltage-Gated K(+)/Na(+) Channels and Scorpion Venom Toxins in Cancer
por: Díaz-García, Alexis, et al.
Publicado: (2020)

Expression and Function of GABA Receptors in Myelinating Cells
por: Serrano-Regal, Mari Paz, et al.
Publicado: (2020)

Tissue-Specific Venom Composition and Differential Gene Expression in Sea Anemones
por: Macrander, Jason, et al.
Publicado: (2016)

The voltage-gated potassium channel Shaker promotes sleep via thermosensitive GABA transmission
por: Kim, Ji-hyung, et al.
Publicado: (2020)

Regulation of GABA(A) Receptors Induced by the Activation of L-Type Voltage-Gated Calcium Channels
por: Gravielle, María Clara
Publicado: (2021)

A Tale of Toxin Promiscuity: The Versatile Pharmacological Effects of Hcr 1b-2 Sea Anemone Peptide on Voltage-Gated Ion Channels
por: Pinheiro-Junior, Ernesto Lopes, et al.
Publicado: (2022)

A Sea Anemone Lebrunia neglecta Venom Fraction Decreases Boar Sperm Cells Capacitation: Possible Involvement of HVA Calcium Channels
por: Lazcano-Pérez, Fernando, et al.
Publicado: (2022)

Toxicity and Potential Pharmacological Activities in the Persian Gulf Venomous Sea Anemone, Stichodactyla haddoni
por: Moghadasi, Ziba, et al.
Publicado: (2018)

Pandinus imperator scorpion venom blocks voltage-gated potassium channels in GH3 cells
por: Pappone, PA, et al.
Publicado: (1988)

Animal Venom Peptides Cause Antinociceptive Effects by Voltage-gated Calcium Channels Activity Blockage
por: Trevisan, Gabriela, et al.
Publicado: (2022)

P2X7 Receptors as a Therapeutic Target in Cerebrovascular Diseases
por: Cisneros-Mejorado, Abraham J., et al.
Publicado: (2020)

Serotherapy against Voltage-Gated Sodium Channel-Targeting α-Toxins from Androctonus Scorpion Venom
por: Martin-Eauclaire, Marie-France, et al.
Publicado: (2019)

Venom in Furs: Facial Masks as Aposematic Signals in a Venomous Mammal
por: Nekaris, K. Anne-Isola, et al.
Publicado: (2019)

K(ca)3.1 Activation Via P2y(2) Purinergic Receptors Promotes Human Ovarian Cancer Cell (Skov-3) Migration
por: Robles-Martínez, L., et al.
Publicado: (2017)

Proteomic analysis of the Theileria annulata schizont
por: Witschi, M., et al.
Publicado: (2013)

Identification of unusual peptides with new Cys frameworks in the venom of the cold-water sea anemone Cnidopus japonicus
por: Babenko, Vladislav V., et al.
Publicado: (2017)

MRI- and histologically derived neuroanatomical atlas of the Ambystoma mexicanum (axolotl)
por: Lazcano, Ivan, et al.
Publicado: (2021)

A subfraction obtained from the venom of the tarantula Poecilotheria regalis contains inhibitor cystine knot peptides and induces relaxation of rat aorta by inhibiting L-type voltage-gated calcium channels
por: Díaz-Peña, Luis Fernando, et al.
Publicado: (2023)

Coupling between Voltage Sensors and Activation Gate in Voltage-gated K(+) Channels
por: Lu, Zhe, et al.
Publicado: (2002)

Population diversity and multiplicity of infection in Theileria annulata
por: Weir, William, et al.
Publicado: (2011)

First Molecular detection of Theileria annulata in Bangladesh
por: MONI, Mst. Ishrat Zerin, et al.
Publicado: (2019)

Analysis of Soluble Protein Contents from the Nematocysts of a Model Sea Anemone Sheds Light on Venom Evolution
por: Moran, Yehu, et al.
Publicado: (2012)

Significant Anticancer Activity of a Venom Fraction Derived from the Persian Gulf Sea Anemone, Stichodactyla haddoni
por: Moghadasi, Ziba, et al.
Publicado: (2020)

GABA(A) Increases Calcium in Subventricular Zone Astrocyte-Like Cells Through L- and T-Type Voltage-Gated Calcium Channels
por: Young, Stephanie Z., et al.
Publicado: (2010)

A new, widespread venomous mammal species: hemolytic activity of Sorex araneus venom is similar to that of Neomys fodiens venom
por: Kowalski, Krzysztof, et al.
Publicado: (2022)

Hysteresis in voltage-gated channels
por: Villalba-Galea, Carlos A.
Publicado: (2016)

Voltage-gated sodium channels assemble and gate as dimers
por: Clatot, Jérôme, et al.
Publicado: (2017)

Structural dynamics determine voltage and pH gating in human voltage-gated proton channel
por: Han, Shuo, et al.
Publicado: (2022)

Identification of a pore-forming protein from sea anemone Anthopleura dowii Verrill (1869) venom by mass spectrometry
por: Ramírez-Carreto, Santos, et al.
Publicado: (2019)

Genetic Diversity and Population Structure of Theileria annulata in Oman
por: Al-Hamidhi, Salama, et al.
Publicado: (2015)

Approaches to vaccination against Theileria parva and Theileria annulata
por: Nene, V., et al.
Publicado: (2016)

Solenodon genome reveals convergent evolution of venom in eulipotyphlan mammals
por: Casewell, Nicholas R., et al.
Publicado: (2019)

Molecular mechanism of voltage sensing in voltage-gated proton channels
por: Gonzalez, Carlos, et al.
Publicado: (2013)

Mechanism of voltage gating in the voltage-sensing phosphatase Ci-VSP
por: Shen, Rong, et al.
Publicado: (2022)

Caution Is Required in Interpretation of Mutations in the Voltage Sensing Domain of Voltage Gated Channels as Evidence for Gating Mechanisms
por: Kariev, Alisher M., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_mn7cb4r1s6hqkokn5ho4jk1p00