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The dynamic properties of a nuclear coactivator binding domain are evolutionarily conserved

Evolution of proteins is constrained by their structure and function. While there is a consensus that the plasticity of intrinsically disordered proteins relaxes the structural constraints on evolution there is a paucity of data on the molecular details of these processes. The Nuclear Coactivator Bi...

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Detalles Bibliográficos
Autores principales: Karlsson, Elin, Sorgenfrei, Frieda A., Andersson, Eva, Dogan, Jakob, Jemth, Per, Chi, Celestine N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967867/
https://www.ncbi.nlm.nih.gov/pubmed/35354917
http://dx.doi.org/10.1038/s42003-022-03217-y