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Focal p53 protein expression and lymphovascular invasion in primary prostate tumors predict metastatic progression

TP53 is one of the most frequently altered genes in prostate cancer. The precise assessment of its focal alterations in primary tumors by immunohistochemistry (IHC) has significantly enhanced its prognosis. p53 protein expression and lymphovascular invasion (LVI) were evaluated for predicting metast...

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Detalles Bibliográficos
Autores principales: Gesztes, William, Schafer, Cara, Young, Denise, Fox, Jesse, Jiang, Jiji, Chen, Yongmei, Kuo, Huai-Ching, Mwamukonda, Kuwong B., Dobi, Albert, Burke, Allen P., Moul, Judd W., McLeod, David G., Rosner, Inger L., Petrovics, Gyorgy, Tan, Shyh-Han, Cullen, Jennifer, Srivastava, Shiv, Sesterhenn, Isabell A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967869/
https://www.ncbi.nlm.nih.gov/pubmed/35354846
http://dx.doi.org/10.1038/s41598-022-08826-5