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METTL14 promotes prostate tumorigenesis by inhibiting THBS1 via an m6A-YTHDF2-dependent mechanism

N6-methyladenine (m6A) is the most predominant RNA modification, which has been shown to be related to many types of cancers. However, understanding of its role in prostate cancer (PCa) is largely unknown. Here, we report an upregulation of METTL14 that was correlated with poor prognosis in PCa pati...

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Detalles Bibliográficos
Autores principales: Wang, Yongjie, Chen, Junfei, Gao, Wei-Qiang, Yang, Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967870/
https://www.ncbi.nlm.nih.gov/pubmed/35354789
http://dx.doi.org/10.1038/s41420-022-00939-0