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METTL14 promotes prostate tumorigenesis by inhibiting THBS1 via an m6A-YTHDF2-dependent mechanism
N6-methyladenine (m6A) is the most predominant RNA modification, which has been shown to be related to many types of cancers. However, understanding of its role in prostate cancer (PCa) is largely unknown. Here, we report an upregulation of METTL14 that was correlated with poor prognosis in PCa pati...
Autores principales: | Wang, Yongjie, Chen, Junfei, Gao, Wei-Qiang, Yang, Ru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967870/ https://www.ncbi.nlm.nih.gov/pubmed/35354789 http://dx.doi.org/10.1038/s41420-022-00939-0 |
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