Irisin protects against vascular calcification by activating autophagy and inhibiting NLRP3-mediated vascular smooth muscle cell pyroptosis in chronic kidney disease

Irisin protects the cardiovascular system against vascular diseases. However, its role in chronic kidney disease (CKD) -associated vascular calcification (VC) and the underlying mechanisms remain unclear. In the present study, we investigated the potential link among Irisin, pyroptosis, and VC under...

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Detalles Bibliográficos
Autores principales: Pang, Qi, Wang, Peiwen, Pan, Yajing, Dong, Xingtong, Zhou, Ting, Song, Xinyu, Zhang, Aihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967887/
https://www.ncbi.nlm.nih.gov/pubmed/35354793
http://dx.doi.org/10.1038/s41419-022-04735-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967887/
https://www.ncbi.nlm.nih.gov/pubmed/35354793
http://dx.doi.org/10.1038/s41419-022-04735-7

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