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Integrating protein copy numbers with interaction networks to quantify stoichiometry in clathrin-mediated endocytosis

Proteins that drive processes like clathrin-mediated endocytosis (CME) are expressed at copy numbers within a cell and across cell types varying from hundreds (e.g. auxilin) to millions (e.g. clathrin). These variations contain important information about function, but without integration with the i...

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Detalles Bibliográficos
Autores principales: Duan, Daisy, Hanson, Meretta, Holland, David O., Johnson, Margaret E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967901/
https://www.ncbi.nlm.nih.gov/pubmed/35354856
http://dx.doi.org/10.1038/s41598-022-09259-w