TRIM46 activates AKT/HK2 signaling by modifying PHLPP2 ubiquitylation to promote glycolysis and chemoresistance of lung cancer cells

The incidence of lung cancer is increasing worldwide. Although great progress in lung cancer treatment has been made, the clinical outcome is still unsatisfactory. Tripartite motif (TRIM)-containing proteins has been shown to be closely related to tumor progression. However, the function of TRIM46 i...

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Detalles Bibliográficos
Autores principales: Tantai, Jicheng, Pan, Xufeng, Chen, Yong, Shen, Yuzhou, Ji, Chunyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967906/
https://www.ncbi.nlm.nih.gov/pubmed/35354796
http://dx.doi.org/10.1038/s41419-022-04727-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967906/
https://www.ncbi.nlm.nih.gov/pubmed/35354796
http://dx.doi.org/10.1038/s41419-022-04727-7

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