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Ablation of Cbl-b and c-Cbl in dendritic cells causes spontaneous liver cirrhosis via altering multiple properties of CD103(+) cDC1s

The Casitas B-lineage lymphoma (Cbl) family proteins are E3 ubiquitin ligases implicated in the regulation of various immune cells. However, their function in dendritic cells (DCs) remains unclear. To investigate the role of Cbl family members in DCs, we created dendritic cell double-deficient Casit...

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Detalles Bibliográficos
Autores principales: Xu, Fei, Liu, Chen, Dong, Yongli, Wu, Wenyan, Xu, Jie, Yan, Yunqiu, Shao, Yu, Hao, Chuangli, Yang, Yi, Zhang, Jinping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967913/
https://www.ncbi.nlm.nih.gov/pubmed/35354799
http://dx.doi.org/10.1038/s41420-022-00953-2