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Disulfiram Transcends ALDH Inhibitory Activity When Targeting Ovarian Cancer Tumor-Initiating Cells

Epithelial ovarian cancer (EOC) is a global health burden and remains the fifth leading cause of cancer related death in women worldwide with the poorest five-year survival rate of the gynecological malignancies. EOC recurrence is considered to be driven by the survival of chemoresistant, stem-like...

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Detalles Bibliográficos
Autores principales: Caminear, Michael W., Harrington, Brittney S., Kamdar, Rahul D., Kruhlak, Michael J., Annunziata, Christina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967967/
https://www.ncbi.nlm.nih.gov/pubmed/35372040
http://dx.doi.org/10.3389/fonc.2022.762820