Cargando…

Shear-responsive boundary-lubricated hydrogels attenuate osteoarthritis

Lipid-based boundary layers formed on liposome-containing hydrogels can facilitate lubrication. However, these boundary layers can be damaged by shear, resulting in decreased lubrication. Here, a shear-responsive boundary-lubricated drug-loaded hydrogel is created by incorporating celecoxib (CLX)-lo...

Descripción completa

Detalles Bibliográficos
Autores principales: Lei, Yiting, Wang, Xingkuan, Liao, Junyi, Shen, Jieliang, Li, Yuling, Cai, Zhengwei, Hu, Ning, Luo, Xiaoji, Cui, Wenguo, Huang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967971/
https://www.ncbi.nlm.nih.gov/pubmed/35415286
http://dx.doi.org/10.1016/j.bioactmat.2022.02.016