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Shear-responsive boundary-lubricated hydrogels attenuate osteoarthritis
Lipid-based boundary layers formed on liposome-containing hydrogels can facilitate lubrication. However, these boundary layers can be damaged by shear, resulting in decreased lubrication. Here, a shear-responsive boundary-lubricated drug-loaded hydrogel is created by incorporating celecoxib (CLX)-lo...
Autores principales: | Lei, Yiting, Wang, Xingkuan, Liao, Junyi, Shen, Jieliang, Li, Yuling, Cai, Zhengwei, Hu, Ning, Luo, Xiaoji, Cui, Wenguo, Huang, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8967971/ https://www.ncbi.nlm.nih.gov/pubmed/35415286 http://dx.doi.org/10.1016/j.bioactmat.2022.02.016 |
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