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First report of computational protein–ligand docking to evaluate susceptibility to HIV integrase inhibitors in HIV-infected Iranian patients

BACKGROUND: Iran has recently included integrase (INT) inhibitors (INTIs) in the first‐line treatment regimen in human immunodeficiency virus (HIV)-infected patients. However, there is no bioinformatics data to elaborate the impact of resistance-associated mutations (RAMs) and naturally occurring po...

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Detalles Bibliográficos
Autores principales: Ghasabi, Farzane, Hashempour, Ava, Khodadad, Nastaran, Bemani, Soudabeh, Keshani, Parisa, Shekiba, Mohamad Javad, Hasanshahi, Zahra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968007/
https://www.ncbi.nlm.nih.gov/pubmed/35368742
http://dx.doi.org/10.1016/j.bbrep.2022.101254