Boost of solubility and supersaturation of celecoxib via synergistic interactions of methacrylic acid-ethyl acrylate copolymer (1:1) and hydroxypropyl cellulose in ternary amorphous solid dispersions

A current trend in the development of amorphous solid dispersions (ASDs) is the combination of two polymers for synergistic enhancement in supersaturation of poorly soluble drugs. We investigated the supersaturation potential of celecoxib (CXB) using combinations of methacrylic acid-ethyl acrylate c...

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Detalles Bibliográficos
Autores principales: Pöstges, Florian, Kayser, Kevin, Stoyanov, Edmont, Wagner, Karl G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968008/
https://www.ncbi.nlm.nih.gov/pubmed/35368508
http://dx.doi.org/10.1016/j.ijpx.2022.100115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968008/
https://www.ncbi.nlm.nih.gov/pubmed/35368508
http://dx.doi.org/10.1016/j.ijpx.2022.100115

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