Lrig1 expression identifies airway basal cells with high proliferative capacity and restricts lung squamous cell carcinoma growth

BACKGROUND: Lung squamous cell carcinoma (LUSC) accounts for a significant proportion of cancer deaths worldwide, and is preceded by the appearance of progressively disorganised pre-invasive lesions in the airway epithelium. Yet the biological mechanisms underlying progression of pre-invasive lesion...

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Detalles Bibliográficos
Autores principales: Succony, Laura, Gómez-López, Sandra, Pennycuick, Adam, Alhendi, Ahmed S.N., Davies, Derek, Clarke, Sarah E., Gowers, Kate H.C., Wright, Nicholas A., Jensen, Kim B., Janes, Sam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2022
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968013/
https://www.ncbi.nlm.nih.gov/pubmed/34385275
http://dx.doi.org/10.1183/13993003.00816-2020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968013/
https://www.ncbi.nlm.nih.gov/pubmed/34385275
http://dx.doi.org/10.1183/13993003.00816-2020

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