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Overexpression of CEACAM6 activates Src-FAK signaling and inhibits anoikis, through homophilic interactions in lung adenocarcinomas

Among carcinoembryonic antigen-related cell adhesion molecule (CEACAM) family proteins, CEACAM6 has received less attention than CEACAM5 and its presence and role in lung cancer are largely unknown. The application of CellphoneDB on the single cell RNA sequencing dataset showed that the homophilic i...

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Detalles Bibliográficos
Autores principales: Kim, Eun Young, Cha, Yoon Jin, Jeong, Sukin, Chang, Yoon Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968058/
https://www.ncbi.nlm.nih.gov/pubmed/35358791
http://dx.doi.org/10.1016/j.tranon.2022.101402