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Case Report: Neratinib Therapy Improves Glycemic Control in a Patient With Type 2 Diabetes and Breast Cancer

A critical decline of functional insulin-producing pancreatic β-cells is the central pathologic element of both type 1 and type 2 diabetes. Mammalian Sterile 20-like kinase 1 (MST1) is a key mediator of β-cell failure and the identification of neratinib as MST1 inhibitor with potent effects on β-cel...

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Detalles Bibliográficos
Autores principales: Angelis, Vasileios, Johnston, Stephen R. D., Ardestani, Amin, Maedler, Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968155/
https://www.ncbi.nlm.nih.gov/pubmed/35370966
http://dx.doi.org/10.3389/fendo.2022.830097