Linking Alzheimer’s Disease and Type 2 Diabetes: Characterization and Inhibition of Cytotoxic Aβ and IAPP Hetero-Aggregates

The cytotoxic self-aggregation of β-amyloid (Aβ) peptide and islet amyloid polypeptide (IAPP) is implicated in the pathogenesis of Alzheimer’s disease (AD) and Type 2 diabetes (T2D), respectively. Increasing evidence, particularly the co-deposition of Aβ and IAPP in both brain and pancreatic tissues...

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Detalles Bibliográficos
Autores principales: Al Adem, Kenana, Shanti, Aya, Srivastava, Amit, Homouz, Dirar, Thomas, Sneha Ann, Khair, Mostafa, Stefanini, Cesare, Chan, Vincent, Kim, Tae-Yeon, Lee, Sungmun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968156/
https://www.ncbi.nlm.nih.gov/pubmed/35372522
http://dx.doi.org/10.3389/fmolb.2022.842582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968156/
https://www.ncbi.nlm.nih.gov/pubmed/35372522
http://dx.doi.org/10.3389/fmolb.2022.842582

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